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脑蛋白CG6抗体

简要描述:脑蛋白CG6抗体免 疫 原;KLH conjugated synthetic peptide derived from human Brain protein CG6: 141-240/344

  • 产品型号:GOY-01K0542
  • 厂商性质:科研
  • 更新时间:2023-10-24 00:00:00
  • 访  问  量:362

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脑蛋白CG6抗体


产品名称

英文名称

货号

脑蛋白CG6抗体

Brain protein CG6

GOY-01K0542

商品属性:

英文名称: Brain protein CG6

中文名:脑蛋白CG6抗体

   名;Brain protein CG 6; Brain protein CG-6; Brain protein CG6; C9orf4; CG 6; CG6; chromosome 9 open reading frame 4; CI004_HUMAN; Uncharacterized protein C9orf4.

研究领域;细胞生物  发育生物学  神经生物学

抗体来源;Rabbit

克隆类型;Polyclonal

交叉反应;(predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )

产品应用;WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理论分子量;37kDa

细胞定位;细胞膜

   状;Liquid

   度;1mg/ml

原;KLH conjugated synthetic peptide derived from human Brain protein CG6: 141-240/344

   型;IgG

纯化方法;affinity purified by Protein A

液;0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

注意事项;This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍:

C9orf4 is a 344 amino acid single-pass membrane protein that is primarily expressed in adult and fetal brain and is weakly expressed in spinal cord, adult ovary and medulla. C9orf4 contains one DOMON domain, a predominantly β-sheet domain that is thought to aide in extracellular adhesion. The gene encoding C9orf4 maps to human chromosome 9, which consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.

Component of the outer core of AMPAR complex. AMPARcomplex consists of an inner core made of 4 pore-forming GluA/GRIAproteins (GRIA1, GRIA2, GRIA3 and GRIA4) and 4 major auxiliarysubunits arranged in a twofold symmetry. One of the two pairs ofdistinct binding sites is occupied either by CNIH2, CNIH3 orCACNG2, CACNG3. The other harbors CACNG2, CACNG3, CACNG4, CACNG8 orGSG1L. This inner core of AMPAR complex is complemented by outercore constituents binding directly to the GluA/GRIA proteins atsites distinct from the interaction sites of the inner coreconstituents. Outer core constituents include at least PRRT1,PRRT2, CKAMP44/SHISA9, FRRS1L and NRN1. The proteins of the innerand outer core serve as a platform for other, more peripherallyassociated AMPAR constituents. Alone or in combination, theseauxiliary subunits control the gating and pharmacology of the AMPARcomplex and profoundly impact their biogenesis and proteinprocessing (By similarity).

 

 

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多克隆抗体制备:

我公司合成抗原,保证阳性血清和抗体ELISA效价达到1:32000,由蛋白抗原制备的多抗,保证WB检测结果是阳性。技术服务实行分步报价,按节点收费,为客户节约成本。

鼠单克隆抗体制备:

客户可根据项目实际需求情况灵活选择进行,我公司将为您的项目提供专业的建议。在制备过程中,与客户互动验证,确保最终制备的抗体ELISA阳性血清检测达到合同要求的同时,也能满足客户抗体最终应用验证需求。技术服务实行分步报价,按节点收费,为客户节约成本。

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重组抗体表达服务:

重组抗体技术使制备人源化抗体和人源抗体成为可能,而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台,能为客户提供各种类型的重组抗体表达服务,包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达,抗体人源化改造及表达等服务。

单项免疫学及检测服务:

我公司也为客户提供单项免疫学和检测服务,如动物免疫、动物饲养、抗体修饰服务(如FITC,HRP等的标记)、以及ELISA,WB,IHC,DB等检测服务。

抗体定制服务:

已注册商标,主要用于抗体药物发现和开发,是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务,主要面向工业客户。

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