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精子尾部结构蛋白抗体

简要描述:精子尾部结构蛋白抗体免 疫 原;KLH conjugated synthetic peptide derived from human Cenexin1: 1-100/829

  • 产品型号:GOY-01K0289
  • 厂商性质:科研
  • 更新时间:2023-10-24 00:00:00
  • 访  问  量:129

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精子尾部结构蛋白抗体


产品名称

英文名称

货号

精子尾部结构蛋白抗体

Cenexin1

GOY-01K0289

商品属性:

英文名称: Cenexin1

中文名:精子尾部结构蛋白抗体

    名;Cenexin1/ODF2; sperm tail structural protein; 84 kDa outer dense fiber protein; Cenexin 1; Cenexin1 variant 1; KKT 4; KKT4; ODF 2; ODF 84; ODF2; ODF2/1; ODF2/2; ODF84; Outer dense fiber of sperm tail 2; Outer dense fiber of sperm tails 2; outer dense fiber of sperm tails; Outer dense fiber of sperm tails protein 2; Outer dense fiber of sperm tails, 84 kD; Outer dense fiber protein 2; Sperm outer dense fiber major protein 2; Testis specific autoantigen; ODFP2_HUMAN.

研究领域;免疫学  发育生物学  信号转导

抗体来源;Rabbit

克隆类型;Polyclonal

交叉反应;Rat,  (predicted: Human, )

产品应用;WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理论分子量;91kDa

细胞定位;细胞浆

    状;Liquid

    度;1mg/ml

免 疫 原;KLH conjugated synthetic peptide derived from human Cenexin1: 1-100/829

    型;IgG

纯化方法;affinity purified by Protein A

缓 冲 液;0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

注意事项;This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍:

Cenexin1 is an isoform of ODF2, that unlike ODF2  is present in several somatic cell types. Cenexin1 acts as a general scaffold  protein that is specifically localised to the distal/subdistal appendages of  mother centrioles. Cenexin1 is required for proper localization of Plk1 to  the centrosomes. This centrosomal localization of Plk1 is required for proper  microtubule function. Cenexin1 recruits Plk1 via a C-terminal extension of  cenexin1 that is not present in ODF2. Cenexin1 is required for proper mitotic  progression; depletion of Cenexin1 ultimately leads to chromosome  missegregation and apoptosis. The ODF2 (outer dense fiber 2) gene encodes  both ODF2 and Cenexin1, which have very different functions. ODF2 is a major  component of sperm tail outer dense fibers (ODFs). ODFs are filamentous  structures located on the outside of the axoneme in the midpiece and  principal piece of the mammalian sperm tail. They may help to maintain the  passive elastic structures and elastic recoil of the sperm tail, and may also  modulate sperm motility.

Seems to be a major component of sperm tail outer  dense fibers (ODF). ODFs are filamentous structures located on the outside of  the axoneme in the midpiece and principal piece of the mammalian sperm tail  and may help to maintain the passive elastic structures and elastic recoil of  the sperm tail. May have a modulating influence on sperm motility. Functions  as a general scaffold protein that is specifically localized at the  distal/subdistal appendages of mother centrioles. Component of the centrosome  matrix required for the localization of PLK1 and NIN to the centrosomes.  Required for the formation and/or maintenance of normal CETN1 assembly.

 

 

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多克隆抗体制备:

我公司合成抗原,保证阳性血清和抗体ELISA效价达到1:32000,由蛋白抗原制备的多抗,保证WB检测结果是阳性。技术服务实行分步报价,按节点收费,为客户节约成本。

鼠单克隆抗体制备:

客户可根据项目实际需求情况灵活选择进行,我公司将为您的项目提供专业的建议。在制备过程中,与客户互动验证,确保最终制备的抗体ELISA阳性血清检测达到合同要求的同时,也能满足客户抗体最终应用验证需求。技术服务实行分步报价,按节点收费,为客户节约成本。

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重组抗体表达服务:

重组抗体技术使制备人源化抗体和人源抗体成为可能,而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台,能为客户提供各种类型的重组抗体表达服务,包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达,抗体人源化改造及表达等服务。

单项免疫学及检测服务:

我公司也为客户提供单项免疫学和检测服务,如动物免疫、动物饲养、抗体修饰服务(如FITC,HRP等的标记)、以及ELISA,WB,IHC,DB等检测服务。

抗体定制服务:

已注册商标,主要用于抗体药物发现和开发,是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务,主要面向工业客户。

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