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S100钙结合蛋白A12抗体
产品名称 | 英文名称 | 货号 |
S100钙结合蛋白A12抗体 | S100A12 | GOY-01K2574 |
商品属性：
英文名称: S100A12
中文名:S100钙结合蛋白A12抗体
别 名；CAAF1; CAGC;
Calcitermin; Calcium binding protein in amniotic fluid; Calcium-binding protein
in amniotic fluid 1; Calgranulin C; Calgranulin related protein; Calgranulin-C;
CGRP; EN RAGE; EN-RAGE; ENRAGE; Extracellular newly identified RAGE-binding
protein; MRP6; Neutrophil S100 protein; p6; Protein S100 A12; S100 calcium
binding protein A12; S100 calcium-binding protein A12; S100A12; S10AC_HUMAN.
研究领域；细胞生物 信号转导 细胞周期蛋白 转运蛋白 细胞分化 细胞骨架
抗体来源；Rabbit
克隆类型；Polyclonal
交叉反应；(predicted:
Human, )
产品应用；ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量；10kDa
细胞定位；细胞膜 细胞外基质 分泌型蛋白
性 状；Liquid
浓 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human S100A12: 2-60/92
亚 型；IgG
纯化方法；affinity
purified by Protein A
缓 冲 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事项；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产品介绍:
The protein encoded by this gene is a member of
the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100
proteins are localized in the cytoplasm and/or nucleus of a wide range of
cells, and involved in the regulation of a number of cellular processes such
as cell cycle progression and differentiation. S100 genes include at least 13
members which are located as a cluster on chromosome 1q21. This protein is
proposed to be involved in specific calcium-dependent signal transduction
pathways and its regulatory effect on cytoskeletal components may modulate
various neutrophil activities. [provided by RefSeq, Jul 2008] Calcitermin possesses antifungal activity against
C.albicans and is also active against E.coli and P.aeruginosa but not
L.monocytogenes and S.aureus. Binds calcium, zinc and copper. Presence of
zinc increases the affinity for calcium. Plays an important role in the
inflammatory response. Interaction with AGER on endothelium, mononuclear
phagocytes, and lymphocytes triggers cellular activation, with generation of
key proinflammatory mediators. |
多克隆抗体制备：
我公司合成抗原，保证阳性血清和抗体ELISA效价达到1：32000，由蛋白抗原制备的多抗，保证WB检测结果是阳性。技术服务实行分步报价，按节点收费，为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行，我公司将为您的项目提供专业的建议。在制备过程中，与客户互动验证，确保最终制备的抗体ELISA阳性血清检测达到合同要求的同时，也能满足客户抗体最终应用验证需求。技术服务实行分步报价，按节点收费，为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能，而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台，能为客户提供各种类型的重组抗体表达服务，包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达，抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务，如动物免疫、动物饲养、抗体修饰服务（如FITC，HRP等的标记）、以及ELISA，WB，IHC，DB等检测服务。
抗体定制服务:
已注册商标，主要用于抗体药物发现和开发，是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务，主要面向工业客户。
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