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轴突导向因子SEMA6C抗体

简要描述：轴突导向因子SEMA6C抗体免疫原；KLH conjugated synthetic peptide derived from human SEMA6C: 256-305/930

产品型号：GOY-01K0633
厂商性质：科研
更新时间：2023-10-24 00:00:00
访问量：33

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轴突导向因子SEMA6C抗体

产品名称	英文名称	货号
轴突导向因子SEMA6C抗体	SEMA6C	GOY-01K0633

商品属性：

英文名称: SEMA6C

中文名:轴突导向因子SEMA6C抗体

别名；KIAA1869; m Sema Y; m Sema Y2; sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C; Sema Y antibody Semaphorin 6C [Precursor]; Semaphorin Y; SEMAY; SEM6C_HUMAN.

研究领域；细胞生物神经生物学细胞分化细胞膜蛋白

抗体来源；Rabbit

克隆类型；Polyclonal

交叉反应；(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )

产品应用；WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理论分子量；97kDa

细胞定位；细胞膜

性状；Liquid

浓度；1mg/ml

免疫原；KLH conjugated synthetic peptide derived from human SEMA6C: 256-305/930 <Extracellular>

亚型；IgG

纯化方法；affinity purified by Protein A

保存条件；Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

注意事项；This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍:

Semaphorins are a family of cell surface and secreted proteins involved in neural development that are conserved from insects to humans. Members of this family are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular “semaphorin” domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. The transmembrane semaphorins are characterized by an additional 80 amino acid transmembrane domain and an 80-110 amino acid cytoplasmic domain. SEMA6C, also known as SEMA Y, is a transmembrane protein expressed in fetal brain and adult skeletal muscle. Three isoforms of this semaphorin exist due to alternative splicing: SEMA6C 1, SEMA6C 2 and SEMA6C 3. The extracellular domain of SEMA6C induces growth cone collapse of dorsal root ganglion and plays a role in generation or stability of entorhino-hippocampal synapses.

Function:

SEMA6C belongs to a subfamily characterized by an extracellular semaphorin domain, a transmembrane domain, and a long cytoplasmic tail. Members of this class can repel sympathetic and dorsal root ganglion axons in vitro, consistent with a traditional role as guidance signals. SEMA6C shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro and may be a stop signal for the DRG neurons in their target areas, and possibly also for other neurons. SEMA6C may also be involved in the maintenance and remodeling of neuronal connections.

多克隆抗体制备：

我公司合成抗原，保证阳性血清和抗体ELISA效价达到1：32000，由蛋白抗原制备的多抗，保证WB检测结果是阳性。技术服务实行分步报价，按节点收费，为客户节约成本。

鼠单克隆抗体制备:

客户可根据项目实际需求情况灵活选择进行，我公司将为您的项目提供专业的建议。在制备过程中，与客户互动验证，确保最终制备的抗体ELISA阳性血清检测达到合同要求的同时，也能满足客户抗体最终应用验证需求。技术服务实行分步报价，按节点收费，为客户节约成本。

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重组抗体表达服务:

重组抗体技术使制备人源化抗体和人源抗体成为可能，而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台，能为客户提供各种类型的重组抗体表达服务，包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达，抗体人源化改造及表达等服务。

单项免疫学及检测服务:

我公司也为客户提供单项免疫学和检测服务，如动物免疫、动物饲养、抗体修饰服务（如FITC，HRP等的标记）、以及ELISA，WB，IHC，DB等检测服务。

抗体定制服务:

已注册商标，主要用于抗体药物发现和开发，是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务，主要面向工业客户。

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轴突导向因子SEMA6C抗体

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